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Invasive Malignant Neoplasm

MedGen UID:
195652
•Concept ID:
C0677898
•
Neoplastic Process
Synonym: Infiltrating Malignant Neoplasm

Definition

Cancer that has spread beyond the layer of tissue in which it developed and is growing into surrounding, healthy tissues. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVInvasive Malignant Neoplasm

Professional guidelines

PubMed

2023 European Thyroid Association Clinical Practice Guidelines for thyroid nodule management.
Durante C, Hegedüs L, Czarniecka A, Paschke R, Russ G, Schmitt F, Soares P, Solymosi T, Papini E
Eur Thyroid J 2023 Oct 1;12(5) Epub 2023 Aug 14 doi: 10.1530/ETJ-23-0067. PMID: 37358008Free PMC Article
Gastric cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up.
Lordick F, Carneiro F, Cascinu S, Fleitas T, Haustermans K, Piessen G, Vogel A, Smyth EC; ESMO Guidelines Committee. Electronic address: clinicalguidelines@esmo.org
Ann Oncol 2022 Oct;33(10):1005-1020. Epub 2022 Jul 29 doi: 10.1016/j.annonc.2022.07.004. PMID: 35914639
Revisions of international consensus Fukuoka guidelines for the management of IPMN of the pancreas.
Tanaka M, Fernández-Del Castillo C, Kamisawa T, Jang JY, Levy P, Ohtsuka T, Salvia R, Shimizu Y, Tada M, Wolfgang CL
Pancreatology 2017 Sep-Oct;17(5):738-753. Epub 2017 Jul 13 doi: 10.1016/j.pan.2017.07.007. PMID: 28735806

Recent clinical studies

Etiology

Assessment of Regional Variability in COVID-19 Outcomes Among Patients With Cancer in the United States.
Hawley JE, Sun T, Chism DD, Duma N, Fu JC, Gatson NTN, Mishra S, Nguyen RH, Reid SA, Serrano OK, Singh SRK, Venepalli NK, Bakouny Z, Bashir B, Bilen MA, Caimi PF, Choueiri TK, Dawsey SJ, Fecher LA, Flora DB, Friese CR, Glover MJ, Gonzalez CJ, Goyal S, Halfdanarson TR, Hershman DL, Khan H, Labaki C, Lewis MA, McKay RR, Messing I, Pennell NA, Puc M, Ravindranathan D, Rhodes TD, Rivera AV, Roller J, Schwartz GK, Shah SA, Shaya JA, Streckfuss M, Thompson MA, Wulff-Burchfield EM, Xie Z, Yu PP, Warner JL, Shah DP, French B, Hwang C; COVID-19 and Cancer Consortium (CCC19)
JAMA Netw Open 2022 Jan 4;5(1):e2142046. doi: 10.1001/jamanetworkopen.2021.42046. PMID: 34982158Free PMC Article
Knockdown of eukaryotic translation initiation factor 5A2 enhances the therapeutic efficiency of doxorubicin in hepatocellular carcinoma cells by triggering lethal autophagy.
Tang Y, Chen K, Luan X, Zhang J, Liu R, Zheng X, Xie S, Ke H, Zhang X, Chen W
Int J Oncol 2020 Dec;57(6):1368-1380. Epub 2020 Nov 2 doi: 10.3892/ijo.2020.5143. PMID: 33174013Free PMC Article
Temporomandibular joint, skull base and mandibular ramus functional reconstruction with homologous bank tissue and free flap: a case report with 30 months follow-up.
Maranzano M, Rizzo R, Cicognini A, Sorato R, Recchia G, De Grazia R, Di Paola F, Paolin A, Mazzoleni G
Microsurgery 2010;30(1):73-8. doi: 10.1002/micr.20694. PMID: 19670240
Laryngeal granuloma: characteristics of the covering epithelium.
Luzar B, Gale N, Klopcic U, Fischinger J
J Laryngol Otol 2000 Apr;114(4):264-7. doi: 10.1258/0022215001905526. PMID: 10845040

Diagnosis

Assessment of Regional Variability in COVID-19 Outcomes Among Patients With Cancer in the United States.
Hawley JE, Sun T, Chism DD, Duma N, Fu JC, Gatson NTN, Mishra S, Nguyen RH, Reid SA, Serrano OK, Singh SRK, Venepalli NK, Bakouny Z, Bashir B, Bilen MA, Caimi PF, Choueiri TK, Dawsey SJ, Fecher LA, Flora DB, Friese CR, Glover MJ, Gonzalez CJ, Goyal S, Halfdanarson TR, Hershman DL, Khan H, Labaki C, Lewis MA, McKay RR, Messing I, Pennell NA, Puc M, Ravindranathan D, Rhodes TD, Rivera AV, Roller J, Schwartz GK, Shah SA, Shaya JA, Streckfuss M, Thompson MA, Wulff-Burchfield EM, Xie Z, Yu PP, Warner JL, Shah DP, French B, Hwang C; COVID-19 and Cancer Consortium (CCC19)
JAMA Netw Open 2022 Jan 4;5(1):e2142046. doi: 10.1001/jamanetworkopen.2021.42046. PMID: 34982158Free PMC Article
Knockdown of eukaryotic translation initiation factor 5A2 enhances the therapeutic efficiency of doxorubicin in hepatocellular carcinoma cells by triggering lethal autophagy.
Tang Y, Chen K, Luan X, Zhang J, Liu R, Zheng X, Xie S, Ke H, Zhang X, Chen W
Int J Oncol 2020 Dec;57(6):1368-1380. Epub 2020 Nov 2 doi: 10.3892/ijo.2020.5143. PMID: 33174013Free PMC Article
Epidermotropic metastatic mucoepidermoid carcinoma.
Abbas O, Reddy K, Demierre MF, Blanchard RA, Mahalingam M
Am J Dermatopathol 2010 Jul;32(5):505-8. doi: 10.1097/DAD.0b013e3181c956e1. PMID: 20489572
Sclerosing paraganglioma: report of 19 cases of an unusual variant of neuroendocrine tumor that may be mistaken for an aggressive malignant neoplasm.
Plaza JA, Wakely PE Jr, Moran C, Fletcher CD, Suster S
Am J Surg Pathol 2006 Jan;30(1):7-12. doi: 10.1097/01.pas.0000174012.37439.c7. PMID: 16330936
Reduction mammaplasty in granular cell tumour of the breast.
Bauerfeind I, Ditsch N, Sittek H, Diebold J
Br J Plast Surg 2004 Jul;57(5):458-61. doi: 10.1016/j.bjps.2003.12.019. PMID: 15191830

Therapy

Knockdown of eukaryotic translation initiation factor 5A2 enhances the therapeutic efficiency of doxorubicin in hepatocellular carcinoma cells by triggering lethal autophagy.
Tang Y, Chen K, Luan X, Zhang J, Liu R, Zheng X, Xie S, Ke H, Zhang X, Chen W
Int J Oncol 2020 Dec;57(6):1368-1380. Epub 2020 Nov 2 doi: 10.3892/ijo.2020.5143. PMID: 33174013Free PMC Article

Prognosis

Assessment of Regional Variability in COVID-19 Outcomes Among Patients With Cancer in the United States.
Hawley JE, Sun T, Chism DD, Duma N, Fu JC, Gatson NTN, Mishra S, Nguyen RH, Reid SA, Serrano OK, Singh SRK, Venepalli NK, Bakouny Z, Bashir B, Bilen MA, Caimi PF, Choueiri TK, Dawsey SJ, Fecher LA, Flora DB, Friese CR, Glover MJ, Gonzalez CJ, Goyal S, Halfdanarson TR, Hershman DL, Khan H, Labaki C, Lewis MA, McKay RR, Messing I, Pennell NA, Puc M, Ravindranathan D, Rhodes TD, Rivera AV, Roller J, Schwartz GK, Shah SA, Shaya JA, Streckfuss M, Thompson MA, Wulff-Burchfield EM, Xie Z, Yu PP, Warner JL, Shah DP, French B, Hwang C; COVID-19 and Cancer Consortium (CCC19)
JAMA Netw Open 2022 Jan 4;5(1):e2142046. doi: 10.1001/jamanetworkopen.2021.42046. PMID: 34982158Free PMC Article
Knockdown of eukaryotic translation initiation factor 5A2 enhances the therapeutic efficiency of doxorubicin in hepatocellular carcinoma cells by triggering lethal autophagy.
Tang Y, Chen K, Luan X, Zhang J, Liu R, Zheng X, Xie S, Ke H, Zhang X, Chen W
Int J Oncol 2020 Dec;57(6):1368-1380. Epub 2020 Nov 2 doi: 10.3892/ijo.2020.5143. PMID: 33174013Free PMC Article
Temporomandibular joint, skull base and mandibular ramus functional reconstruction with homologous bank tissue and free flap: a case report with 30 months follow-up.
Maranzano M, Rizzo R, Cicognini A, Sorato R, Recchia G, De Grazia R, Di Paola F, Paolin A, Mazzoleni G
Microsurgery 2010;30(1):73-8. doi: 10.1002/micr.20694. PMID: 19670240

Clinical prediction guides

Assessment of Regional Variability in COVID-19 Outcomes Among Patients With Cancer in the United States.
Hawley JE, Sun T, Chism DD, Duma N, Fu JC, Gatson NTN, Mishra S, Nguyen RH, Reid SA, Serrano OK, Singh SRK, Venepalli NK, Bakouny Z, Bashir B, Bilen MA, Caimi PF, Choueiri TK, Dawsey SJ, Fecher LA, Flora DB, Friese CR, Glover MJ, Gonzalez CJ, Goyal S, Halfdanarson TR, Hershman DL, Khan H, Labaki C, Lewis MA, McKay RR, Messing I, Pennell NA, Puc M, Ravindranathan D, Rhodes TD, Rivera AV, Roller J, Schwartz GK, Shah SA, Shaya JA, Streckfuss M, Thompson MA, Wulff-Burchfield EM, Xie Z, Yu PP, Warner JL, Shah DP, French B, Hwang C; COVID-19 and Cancer Consortium (CCC19)
JAMA Netw Open 2022 Jan 4;5(1):e2142046. doi: 10.1001/jamanetworkopen.2021.42046. PMID: 34982158Free PMC Article
Knockdown of eukaryotic translation initiation factor 5A2 enhances the therapeutic efficiency of doxorubicin in hepatocellular carcinoma cells by triggering lethal autophagy.
Tang Y, Chen K, Luan X, Zhang J, Liu R, Zheng X, Xie S, Ke H, Zhang X, Chen W
Int J Oncol 2020 Dec;57(6):1368-1380. Epub 2020 Nov 2 doi: 10.3892/ijo.2020.5143. PMID: 33174013Free PMC Article
Laryngeal granuloma: characteristics of the covering epithelium.
Luzar B, Gale N, Klopcic U, Fischinger J
J Laryngol Otol 2000 Apr;114(4):264-7. doi: 10.1258/0022215001905526. PMID: 10845040

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