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Disorder of female genital system

MedGen UID:
9003
•Concept ID:
C0017411
•
Disease or Syndrome
Synonyms: Diseases, Female Genital; Diseases, Gynecologic; Female Genital Disease; Female Genital Diseases; Genital Disease, Female; Genital Diseases, Female; Gynecologic Disease; Gynecologic Diseases
SNOMED CT: Disease of female genital organ (244938009); Disorder of female genital organs (244938009); Disorder of female genital system (310789003); Disorder of female genital tract (310789003); Disease of female genital system (310789003); Gynecological disease (310789003)

Definition

Pathological processes involving the female reproductive tract (GENITALIA, FEMALE). [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDisorder of female genital system

Professional guidelines

PubMed

Recommendations from the 2023 international evidence-based guideline for the assessment and management of polycystic ovary syndrome.
Teede HJ, Tay CT, Laven JJE, Dokras A, Moran LJ, Piltonen TT, Costello MF, Boivin J, Redman LM, Boyle JA, Norman RJ, Mousa A, Joham AE; International PCOS Network
Eur J Endocrinol 2023 Aug 2;189(2):G43-G64. doi: 10.1093/ejendo/lvad096. PMID: 37580861
Recommendations From the 2023 International Evidence-based Guideline for the Assessment and Management of Polycystic Ovary Syndrome.
Teede HJ, Tay CT, Laven JJE, Dokras A, Moran LJ, Piltonen TT, Costello MF, Boivin J, Redman LM, Boyle JA, Norman RJ, Mousa A, Joham AE
J Clin Endocrinol Metab 2023 Sep 18;108(10):2447-2469. doi: 10.1210/clinem/dgad463. PMID: 37580314Free PMC Article
Management of Symptomatic Uterine Leiomyomas: ACOG Practice Bulletin, Number 228.
Obstet Gynecol 2021 Jun 1;137(6):e100-e115. doi: 10.1097/AOG.0000000000004401. PMID: 34011888

Recent clinical studies

Etiology

Genital Ulcers: Differential Diagnosis and Management.
Roett MA
Am Fam Physician 2020 Mar 15;101(6):355-361. PMID: 32163252
Acute Pelvic Pain.
Dewey K, Wittrock C
Emerg Med Clin North Am 2019 May;37(2):207-218. doi: 10.1016/j.emc.2019.01.012. PMID: 30940367
Reassessing hysterectomy.
Stewart EA, Shuster LT, Rocca WA
Minn Med 2012 Mar;95(3):36-9. PMID: 22611818Free PMC Article
Lichen sclerosus.
Powell JJ, Wojnarowska F
Lancet 1999 May 22;353(9166):1777-83. doi: 10.1016/s0140-6736(98)08228-2. PMID: 10348006
Genital psoriasis.
Farber EM, Nall L
Cutis 1992 Oct;50(4):263-6. PMID: 1424790

Diagnosis

Genital Ulcers: Differential Diagnosis and Management.
Roett MA
Am Fam Physician 2020 Mar 15;101(6):355-361. PMID: 32163252
Urogenital infections.
Wagenlehner F
World J Urol 2020 Jan;38(1):1-2. doi: 10.1007/s00345-019-03039-4. PMID: 31788716
Genitourinary Procedures.
Jones MP, Mekuria K
Emerg Med Clin North Am 2019 Nov;37(4):811-819. doi: 10.1016/j.emc.2019.07.014. PMID: 31563209
Female Nonobstetric Genitourinary Emergencies.
Mahonski S, Hu KM
Emerg Med Clin North Am 2019 Nov;37(4):771-784. doi: 10.1016/j.emc.2019.07.012. PMID: 31563207
Genital psoriasis.
Farber EM, Nall L
Cutis 1992 Oct;50(4):263-6. PMID: 1424790

Therapy

Rare Gynecologic Tumors: Coming of Age.
Gershenson DM, Okamoto A, Ray-Coquard I
Gynecol Oncol 2020 Apr;157(1):1-2. doi: 10.1016/j.ygyno.2020.03.001. PMID: 32241340
Primary cytoreductive surgery with or without hyperthermic intraperitoneal chemotherapy (HIPEC) for FIGO stage III epithelial ovarian cancer: OVHIPEC-2, a phase III randomized clinical trial.
Koole S, van Stein R, Sikorska K, Barton D, Perrin L, Brennan D, Zivanovic O, Mosgaard BJ, Fagotti A, Colombo PE, Sonke G, Driel WJV; OVHIPEC-2 Steering Committee and the Dutch OVHIPEC group
Int J Gynecol Cancer 2020 Jun;30(6):888-892. Epub 2020 Mar 23 doi: 10.1136/ijgc-2020-001231. PMID: 32205449Free PMC Article
Surgical approach to hysterectomy for benign gynaecological disease.
Aarts JW, Nieboer TE, Johnson N, Tavender E, Garry R, Mol BW, Kluivers KB
Cochrane Database Syst Rev 2015 Aug 12;2015(8):CD003677. doi: 10.1002/14651858.CD003677.pub5. PMID: 26264829Free PMC Article
Robot-assisted surgery in gynaecology.
Liu H, Lawrie TA, Lu D, Song H, Wang L, Shi G
Cochrane Database Syst Rev 2014 Dec 10;2014(12):CD011422. doi: 10.1002/14651858.CD011422. PMID: 25493418Free PMC Article
2-methoxyestradiol and disorders of female reproductive tissues.
Pinto MP, Medina RA, Owen GI
Horm Cancer 2014 Oct;5(5):274-83. Epub 2014 Apr 25 doi: 10.1007/s12672-014-0181-2. PMID: 24764201Free PMC Article

Prognosis

Modern treatment of vulvar cancer.
Merlo S
Radiol Oncol 2020 Sep 22;54(4):371-376. doi: 10.2478/raon-2020-0053. PMID: 32960779Free PMC Article
Cesarean section one hundred years 1920-2020: the Good, the Bad and the Ugly.
Antoine C, Young BK
J Perinat Med 2020 Sep 4;49(1):5-16. doi: 10.1515/jpm-2020-0305. PMID: 32887190
A Review of Cervical Cancer: Incidence and Disparities.
Buskwofie A, David-West G, Clare CA
J Natl Med Assoc 2020 Apr;112(2):229-232. Epub 2020 Apr 8 doi: 10.1016/j.jnma.2020.03.002. PMID: 32278478
Estimates of incidence and mortality of cervical cancer in 2018: a worldwide analysis.
Arbyn M, Weiderpass E, Bruni L, de Sanjosé S, Saraiya M, Ferlay J, Bray F
Lancet Glob Health 2020 Feb;8(2):e191-e203. Epub 2019 Dec 4 doi: 10.1016/S2214-109X(19)30482-6. PMID: 31812369Free PMC Article
Risk factors for endometrial cancer: An umbrella review of the literature.
Raglan O, Kalliala I, Markozannes G, Cividini S, Gunter MJ, Nautiyal J, Gabra H, Paraskevaidis E, Martin-Hirsch P, Tsilidis KK, Kyrgiou M
Int J Cancer 2019 Oct 1;145(7):1719-1730. Epub 2019 Feb 20 doi: 10.1002/ijc.31961. PMID: 30387875

Clinical prediction guides

Adnexal Lesion Imaging: Past, Present, and Future.
Sadowski EA, Rockall A, Thomassin-Naggara I, Barroilhet LM, Wallace SK, Jha P, Gupta A, Shinagare AB, Guo Y, Reinhold C
Radiology 2023 Jun;307(5):e223281. Epub 2023 May 9 doi: 10.1148/radiol.223281. PMID: 37158725
Diet and Nutrition in Gynecological Disorders: A Focus on Clinical Studies.
Afrin S, AlAshqar A, El Sabeh M, Miyashita-Ishiwata M, Reschke L, Brennan JT, Fader A, Borahay MA
Nutrients 2021 May 21;13(6) doi: 10.3390/nu13061747. PMID: 34063835Free PMC Article
Genital Ulcers: Differential Diagnosis and Management.
Roett MA
Am Fam Physician 2020 Mar 15;101(6):355-361. PMID: 32163252
Reassessing hysterectomy.
Stewart EA, Shuster LT, Rocca WA
Minn Med 2012 Mar;95(3):36-9. PMID: 22611818Free PMC Article
Criteria for diagnosis of Behçet's disease. International Study Group for Behçet's Disease.
Lancet 1990 May 5;335(8697):1078-80. PMID: 1970380

Recent systematic reviews

Global and regional estimates of genital human papillomavirus prevalence among men: a systematic review and meta-analysis.
Bruni L, Albero G, Rowley J, Alemany L, Arbyn M, Giuliano AR, Markowitz LE, Broutet N, Taylor M
Lancet Glob Health 2023 Sep;11(9):e1345-e1362. doi: 10.1016/S2214-109X(23)00305-4. PMID: 37591583Free PMC Article
Role of human papillomavirus (HPV) vaccination on HPV infection and recurrence of HPV related disease after local surgical treatment: systematic review and meta-analysis.
Kechagias KS, Kalliala I, Bowden SJ, Athanasiou A, Paraskevaidi M, Paraskevaidis E, Dillner J, Nieminen P, Strander B, Sasieni P, Veroniki AA, Kyrgiou M
BMJ 2022 Aug 3;378:e070135. doi: 10.1136/bmj-2022-070135. PMID: 35922074Free PMC Article
Endometrial hyperplasia as a risk factor of endometrial cancer.
Nees LK, Heublein S, Steinmacher S, Juhasz-Böss I, Brucker S, Tempfer CB, Wallwiener M
Arch Gynecol Obstet 2022 Aug;306(2):407-421. Epub 2022 Jan 10 doi: 10.1007/s00404-021-06380-5. PMID: 35001185Free PMC Article
EULAR recommendations for women's health and the management of family planning, assisted reproduction, pregnancy and menopause in patients with systemic lupus erythematosus and/or antiphospholipid syndrome.
Andreoli L, Bertsias GK, Agmon-Levin N, Brown S, Cervera R, Costedoat-Chalumeau N, Doria A, Fischer-Betz R, Forger F, Moraes-Fontes MF, Khamashta M, King J, Lojacono A, Marchiori F, Meroni PL, Mosca M, Motta M, Ostensen M, Pamfil C, Raio L, Schneider M, Svenungsson E, Tektonidou M, Yavuz S, Boumpas D, Tincani A
Ann Rheum Dis 2017 Mar;76(3):476-485. Epub 2016 Jul 25 doi: 10.1136/annrheumdis-2016-209770. PMID: 27457513Free PMC Article
The prevalence and phenotypic features of polycystic ovary syndrome: a systematic review and meta-analysis.
Bozdag G, Mumusoglu S, Zengin D, Karabulut E, Yildiz BO
Hum Reprod 2016 Dec;31(12):2841-2855. Epub 2016 Sep 22 doi: 10.1093/humrep/dew218. PMID: 27664216

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