U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from PMC

Abnormal inflammatory response

MedGen UID:
868411
•Concept ID:
C4022805
•
Pathologic Function
HPO: HP:0012647

Definition

Any anomaly of the inflammatory response, a response to injury or infection characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormal inflammatory response

Professional guidelines

PubMed

COPD and biologic treatment: state of the art.
Ferri S, Paoletti G, Pelaia C, Heffler E, Canonica GW, Puggioni F
Curr Opin Allergy Clin Immunol 2023 Aug 1;23(4):309-318. Epub 2023 Jun 20 doi: 10.1097/ACI.0000000000000920. PMID: 37357768
Fecal transplantation for treatment of inflammatory bowel disease.
Imdad A, Pandit NG, Zaman M, Minkoff NZ, Tanner-Smith EE, Gomez-Duarte OG, Acra S, Nicholson MR
Cochrane Database Syst Rev 2023 Apr 25;4(4):CD012774. doi: 10.1002/14651858.CD012774.pub3. PMID: 37094824Free PMC Article
Chronic obstructive pulmonary disease - diagnosis and management of stable disease; a personalized approach to care, using the treatable traits concept based on clinical phenotypes. Position paper of the Czech Pneumological and Phthisiological Society.
Zatloukal J, Brat K, Neumannova K, Volakova E, Hejduk K, Kocova E, Kudela O, Kopecky M, Plutinsky M, Koblizek V
Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2020 Dec;164(4):325-356. doi: 10.5507/bp.2020.056. PMID: 33325455

Recent clinical studies

Etiology

Fecal transplantation for treatment of inflammatory bowel disease.
Imdad A, Pandit NG, Zaman M, Minkoff NZ, Tanner-Smith EE, Gomez-Duarte OG, Acra S, Nicholson MR
Cochrane Database Syst Rev 2023 Apr 25;4(4):CD012774. doi: 10.1002/14651858.CD012774.pub3. PMID: 37094824Free PMC Article
Pediatric sarcoidosis with diagnostic and therapeutical insights.
Sergi CM
Curr Opin Pulm Med 2021 Sep 1;27(5):472-477. doi: 10.1097/MCP.0000000000000814. PMID: 34397614
Recent advances in chronic obstructive pulmonary disease pathogenesis: from disease mechanisms to precision medicine.
Brandsma CA, Van den Berge M, Hackett TL, Brusselle G, Timens W
J Pathol 2020 Apr;250(5):624-635. Epub 2019 Dec 3 doi: 10.1002/path.5364. PMID: 31691283Free PMC Article
Copd.
McIvor RA, Tunks M, Todd DC
BMJ Clin Evid 2011 Jun 6;2011 PMID: 21639960Free PMC Article
Copd.
Kerstjens HA, Postma DS, Ten Hacken N
BMJ Clin Evid 2008 Dec 15;2008 PMID: 19445783Free PMC Article

Diagnosis

COPD and biologic treatment: state of the art.
Ferri S, Paoletti G, Pelaia C, Heffler E, Canonica GW, Puggioni F
Curr Opin Allergy Clin Immunol 2023 Aug 1;23(4):309-318. Epub 2023 Jun 20 doi: 10.1097/ACI.0000000000000920. PMID: 37357768
Expression of MicroRNAs in Sepsis-Related Organ Dysfunction: A Systematic Review.
Maiese A, Scatena A, Costantino A, Chiti E, Occhipinti C, La Russa R, Di Paolo M, Turillazzi E, Frati P, Fineschi V
Int J Mol Sci 2022 Aug 19;23(16) doi: 10.3390/ijms23169354. PMID: 36012630Free PMC Article
Pediatric sarcoidosis with diagnostic and therapeutical insights.
Sergi CM
Curr Opin Pulm Med 2021 Sep 1;27(5):472-477. doi: 10.1097/MCP.0000000000000814. PMID: 34397614
Chronic obstructive pulmonary disease - diagnosis and management of stable disease; a personalized approach to care, using the treatable traits concept based on clinical phenotypes. Position paper of the Czech Pneumological and Phthisiological Society.
Zatloukal J, Brat K, Neumannova K, Volakova E, Hejduk K, Kocova E, Kudela O, Kopecky M, Plutinsky M, Koblizek V
Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2020 Dec;164(4):325-356. doi: 10.5507/bp.2020.056. PMID: 33325455
Biomarkers in COPD.
Tzortzaki EG, Lambiri I, Vlachaki E, Siafakas NM
Curr Med Chem 2007;14(9):1037-48. doi: 10.2174/092986707780362943. PMID: 17439401

Therapy

COPD and biologic treatment: state of the art.
Ferri S, Paoletti G, Pelaia C, Heffler E, Canonica GW, Puggioni F
Curr Opin Allergy Clin Immunol 2023 Aug 1;23(4):309-318. Epub 2023 Jun 20 doi: 10.1097/ACI.0000000000000920. PMID: 37357768
Fecal transplantation for treatment of inflammatory bowel disease.
Imdad A, Pandit NG, Zaman M, Minkoff NZ, Tanner-Smith EE, Gomez-Duarte OG, Acra S, Nicholson MR
Cochrane Database Syst Rev 2023 Apr 25;4(4):CD012774. doi: 10.1002/14651858.CD012774.pub3. PMID: 37094824Free PMC Article
Vitamin D Modulates Intestinal Microbiota in Inflammatory Bowel Diseases.
Battistini C, Ballan R, Herkenhoff ME, Saad SMI, Sun J
Int J Mol Sci 2020 Dec 31;22(1) doi: 10.3390/ijms22010362. PMID: 33396382Free PMC Article
Recent advances in chronic obstructive pulmonary disease pathogenesis: from disease mechanisms to precision medicine.
Brandsma CA, Van den Berge M, Hackett TL, Brusselle G, Timens W
J Pathol 2020 Apr;250(5):624-635. Epub 2019 Dec 3 doi: 10.1002/path.5364. PMID: 31691283Free PMC Article
Copd.
McIvor RA, Tunks M, Todd DC
BMJ Clin Evid 2011 Jun 6;2011 PMID: 21639960Free PMC Article

Prognosis

Expression of MicroRNAs in Sepsis-Related Organ Dysfunction: A Systematic Review.
Maiese A, Scatena A, Costantino A, Chiti E, Occhipinti C, La Russa R, Di Paolo M, Turillazzi E, Frati P, Fineschi V
Int J Mol Sci 2022 Aug 19;23(16) doi: 10.3390/ijms23169354. PMID: 36012630Free PMC Article
The Role of IgG4 in Autoimmunity and Rheumatic Diseases.
Maslinska M, Dmowska-Chalaba J, Jakubaszek M
Front Immunol 2021;12:787422. Epub 2022 Jan 25 doi: 10.3389/fimmu.2021.787422. PMID: 35145508Free PMC Article
Chronic obstructive pulmonary disease - diagnosis and management of stable disease; a personalized approach to care, using the treatable traits concept based on clinical phenotypes. Position paper of the Czech Pneumological and Phthisiological Society.
Zatloukal J, Brat K, Neumannova K, Volakova E, Hejduk K, Kocova E, Kudela O, Kopecky M, Plutinsky M, Koblizek V
Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2020 Dec;164(4):325-356. doi: 10.5507/bp.2020.056. PMID: 33325455
Prognostic factors and risk classifications for patients with metastatic renal cell carcinoma.
Shinohara N, Abe T
Int J Urol 2015 Oct;22(10):888-97. Epub 2015 Jul 5 doi: 10.1111/iju.12858. PMID: 26147084
Pathogenesis of chronic obstructive pulmonary disease.
Macnee W
Clin Chest Med 2007 Sep;28(3):479-513, v. doi: 10.1016/j.ccm.2007.06.008. PMID: 17720039

Clinical prediction guides

Inflammation and vascular dysfunction: The negative synergistic combination of diabetes and COVID-19.
Bolla AM, Loretelli C, Montefusco L, Finzi G, Abdi R, Ben Nasr M, Lunati ME, Pastore I, Bonventre JV, Nebuloni M, Rusconi S, Santus P, Zuccotti G, Galli M, D'Addio F, Fiorina P
Diabetes Metab Res Rev 2022 Oct;38(7):e3565. Epub 2022 Jul 22 doi: 10.1002/dmrr.3565. PMID: 35830597Free PMC Article
Pediatric sarcoidosis with diagnostic and therapeutical insights.
Sergi CM
Curr Opin Pulm Med 2021 Sep 1;27(5):472-477. doi: 10.1097/MCP.0000000000000814. PMID: 34397614
Nrf2 attenuates inflammatory response in COPD/emphysema: Crosstalk with Wnt3a/β-catenin and AMPK pathways.
Cui W, Zhang Z, Zhang P, Qu J, Zheng C, Mo X, Zhou W, Xu L, Yao H, Gao J
J Cell Mol Med 2018 Jul;22(7):3514-3525. Epub 2018 Apr 16 doi: 10.1111/jcmm.13628. PMID: 29659176Free PMC Article
Copd.
McIvor RA, Tunks M, Todd DC
BMJ Clin Evid 2011 Jun 6;2011 PMID: 21639960Free PMC Article
Copd.
Kerstjens HA, Postma DS, Ten Hacken N
BMJ Clin Evid 2008 Dec 15;2008 PMID: 19445783Free PMC Article

Recent systematic reviews

Fecal transplantation for treatment of inflammatory bowel disease.
Imdad A, Pandit NG, Zaman M, Minkoff NZ, Tanner-Smith EE, Gomez-Duarte OG, Acra S, Nicholson MR
Cochrane Database Syst Rev 2023 Apr 25;4(4):CD012774. doi: 10.1002/14651858.CD012774.pub3. PMID: 37094824Free PMC Article
Expression of MicroRNAs in Sepsis-Related Organ Dysfunction: A Systematic Review.
Maiese A, Scatena A, Costantino A, Chiti E, Occhipinti C, La Russa R, Di Paolo M, Turillazzi E, Frati P, Fineschi V
Int J Mol Sci 2022 Aug 19;23(16) doi: 10.3390/ijms23169354. PMID: 36012630Free PMC Article
Computer and mobile technology interventions for self-management in chronic obstructive pulmonary disease.
McCabe C, McCann M, Brady AM
Cochrane Database Syst Rev 2017 May 23;5(5):CD011425. doi: 10.1002/14651858.CD011425.pub2. PMID: 28535331Free PMC Article
Copd.
McIvor RA, Tunks M, Todd DC
BMJ Clin Evid 2011 Jun 6;2011 PMID: 21639960Free PMC Article
Copd.
Kerstjens HA, Postma DS, Ten Hacken N
BMJ Clin Evid 2008 Dec 15;2008 PMID: 19445783Free PMC Article

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...