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T-cell and NK-cell neoplasm

MedGen UID:
277781
•Concept ID:
C1336554
•
Neoplastic Process
Synonyms: T-Cell and NK-Cell Neoplasm; T-Cell Neoplasm; T-cell neoplasm
 
Monarch Initiative: MONDO:0024615

Definition

A group of neoplasms composed of T-lymphocytes and/or NK-cells. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVT-cell and NK-cell neoplasm

Professional guidelines

PubMed

Prophylaxis and management of graft-versus-host disease after stem-cell transplantation for haematological malignancies: updated consensus recommendations of the European Society for Blood and Marrow Transplantation.
Penack O, Marchetti M, Aljurf M, Arat M, Bonifazi F, Duarte RF, Giebel S, Greinix H, Hazenberg MD, Kröger N, Mielke S, Mohty M, Nagler A, Passweg J, Patriarca F, Ruutu T, Schoemans H, Solano C, Vrhovac R, Wolff D, Zeiser R, Sureda A, Peric Z
Lancet Haematol 2024 Feb;11(2):e147-e159. Epub 2024 Jan 3 doi: 10.1016/S2352-3026(23)00342-3. PMID: 38184001
CAR-cell therapy in the era of solid tumor treatment: current challenges and emerging therapeutic advances.
Maalej KM, Merhi M, Inchakalody VP, Mestiri S, Alam M, Maccalli C, Cherif H, Uddin S, Steinhoff M, Marincola FM, Dermime S
Mol Cancer 2023 Jan 30;22(1):20. doi: 10.1186/s12943-023-01723-z. PMID: 36717905Free PMC Article
LGL leukemia: from pathogenesis to treatment.
Lamy T, Moignet A, Loughran TP Jr
Blood 2017 Mar 2;129(9):1082-1094. Epub 2017 Jan 23 doi: 10.1182/blood-2016-08-692590. PMID: 28115367

Recent clinical studies

Etiology

Forks in the road for CAR T and CAR NK cell cancer therapies.
Dagher OK, Posey AD Jr
Nat Immunol 2023 Dec;24(12):1994-2007. Epub 2023 Nov 27 doi: 10.1038/s41590-023-01659-y. PMID: 38012406
Extranodal T- and NK-cell lymphomas.
de Leval L, Feldman AL, Pileri S, Nakamura S, Gaulard P
Virchows Arch 2023 Jan;482(1):245-264. Epub 2022 Nov 7 doi: 10.1007/s00428-022-03434-0. PMID: 36336765Free PMC Article
New concepts in EBV-associated B, T, and NK cell lymphoproliferative disorders.
Quintanilla-Martinez L, Swerdlow SH, Tousseyn T, Barrionuevo C, Nakamura S, Jaffe ES
Virchows Arch 2023 Jan;482(1):227-244. Epub 2022 Oct 11 doi: 10.1007/s00428-022-03414-4. PMID: 36216980Free PMC Article
Identification and Validation of a Novel Signature Based on NK Cell Marker Genes to Predict Prognosis and Immunotherapy Response in Lung Adenocarcinoma by Integrated Analysis of Single-Cell and Bulk RNA-Sequencing.
Song P, Li W, Guo L, Ying J, Gao S, He J
Front Immunol 2022;13:850745. Epub 2022 Jun 10 doi: 10.3389/fimmu.2022.850745. PMID: 35757748Free PMC Article
NK cells and ILCs in tumor immunotherapy.
Sivori S, Pende D, Quatrini L, Pietra G, Della Chiesa M, Vacca P, Tumino N, Moretta F, Mingari MC, Locatelli F, Moretta L
Mol Aspects Med 2021 Aug;80:100870. Epub 2020 Aug 13 doi: 10.1016/j.mam.2020.100870. PMID: 32800530

Diagnosis

Extranodal T- and NK-cell lymphomas.
de Leval L, Feldman AL, Pileri S, Nakamura S, Gaulard P
Virchows Arch 2023 Jan;482(1):245-264. Epub 2022 Nov 7 doi: 10.1007/s00428-022-03434-0. PMID: 36336765Free PMC Article
New concepts in EBV-associated B, T, and NK cell lymphoproliferative disorders.
Quintanilla-Martinez L, Swerdlow SH, Tousseyn T, Barrionuevo C, Nakamura S, Jaffe ES
Virchows Arch 2023 Jan;482(1):227-244. Epub 2022 Oct 11 doi: 10.1007/s00428-022-03414-4. PMID: 36216980Free PMC Article
Classification and diagnostic evaluation of nodal T- and NK-cell lymphomas.
Feldman AL, Laurent C, Narbaitz M, Nakamura S, Chan WC, de Leval L, Gaulard P
Virchows Arch 2023 Jan;482(1):265-279. Epub 2022 Oct 10 doi: 10.1007/s00428-022-03412-6. PMID: 36210383
CAR-NK Cells in the Treatment of Solid Tumors.
Wrona E, Borowiec M, Potemski P
Int J Mol Sci 2021 May 31;22(11) doi: 10.3390/ijms22115899. PMID: 34072732Free PMC Article
Epstein-Barr virus-associated T- and NK-cell lymphoproliferative diseases: an update and diagnostic approach.
Hue SS, Oon ML, Wang S, Tan SY, Ng SB
Pathology 2020 Jan;52(1):111-127. Epub 2019 Nov 22 doi: 10.1016/j.pathol.2019.09.011. PMID: 31767131

Therapy

Overcoming tumor resistance mechanisms in CAR-NK cell therapy.
Valeri A, García-Ortiz A, Castellano E, Córdoba L, Maroto-Martín E, Encinas J, Leivas A, Río P, Martínez-López J
Front Immunol 2022;13:953849. Epub 2022 Aug 3 doi: 10.3389/fimmu.2022.953849. PMID: 35990652Free PMC Article
CAR-NK Cells in the Treatment of Solid Tumors.
Wrona E, Borowiec M, Potemski P
Int J Mol Sci 2021 May 31;22(11) doi: 10.3390/ijms22115899. PMID: 34072732Free PMC Article
NK cell-based cancer immunotherapy: from basic biology to clinical development.
Liu S, Galat V, Galat Y, Lee YKA, Wainwright D, Wu J
J Hematol Oncol 2021 Jan 6;14(1):7. doi: 10.1186/s13045-020-01014-w. PMID: 33407739Free PMC Article
TIGIT as an emerging immune checkpoint.
Harjunpää H, Guillerey C
Clin Exp Immunol 2020 May;200(2):108-119. Epub 2019 Dec 25 doi: 10.1111/cei.13407. PMID: 31828774Free PMC Article
Dendritic cell-derived exosomes for cancer therapy.
Pitt JM, André F, Amigorena S, Soria JC, Eggermont A, Kroemer G, Zitvogel L
J Clin Invest 2016 Apr 1;126(4):1224-32. doi: 10.1172/JCI81137. PMID: 27035813Free PMC Article

Prognosis

Single-cell atlas reveals a distinct immune profile fostered by T cell-B cell crosstalk in triple negative breast cancer.
Ding S, Qiao N, Zhu Q, Tong Y, Wang S, Chen X, Tian Q, Xiao Y, Shen K
Cancer Commun (Lond) 2023 Jun;43(6):661-684. Epub 2023 May 9 doi: 10.1002/cac2.12429. PMID: 37158690Free PMC Article
Identification and Validation of a Novel Signature Based on NK Cell Marker Genes to Predict Prognosis and Immunotherapy Response in Lung Adenocarcinoma by Integrated Analysis of Single-Cell and Bulk RNA-Sequencing.
Song P, Li W, Guo L, Ying J, Gao S, He J
Front Immunol 2022;13:850745. Epub 2022 Jun 10 doi: 10.3389/fimmu.2022.850745. PMID: 35757748Free PMC Article
Tumor-infiltrating lymphocytes in the immunotherapy era.
Paijens ST, Vledder A, de Bruyn M, Nijman HW
Cell Mol Immunol 2021 Apr;18(4):842-859. Epub 2020 Nov 2 doi: 10.1038/s41423-020-00565-9. PMID: 33139907Free PMC Article
NK cells and ILCs in tumor immunotherapy.
Sivori S, Pende D, Quatrini L, Pietra G, Della Chiesa M, Vacca P, Tumino N, Moretta F, Mingari MC, Locatelli F, Moretta L
Mol Aspects Med 2021 Aug;80:100870. Epub 2020 Aug 13 doi: 10.1016/j.mam.2020.100870. PMID: 32800530
CD57 in human natural killer cells and T-lymphocytes.
Kared H, Martelli S, Ng TP, Pender SL, Larbi A
Cancer Immunol Immunother 2016 Apr;65(4):441-52. Epub 2016 Feb 5 doi: 10.1007/s00262-016-1803-z. PMID: 26850637Free PMC Article

Clinical prediction guides

A comprehensive single-cell breast tumor atlas defines epithelial and immune heterogeneity and interactions predicting anti-PD-1 therapy response.
Xu L, Saunders K, Huang SP, Knutsdottir H, Martinez-Algarin K, Terrazas I, Chen K, McArthur HM, Maués J, Hodgdon C, Reddy SM, Roussos Torres ET, Xu L, Chan IS
Cell Rep Med 2024 May 21;5(5):101511. Epub 2024 Apr 12 doi: 10.1016/j.xcrm.2024.101511. PMID: 38614094Free PMC Article
Single-cell atlas reveals a distinct immune profile fostered by T cell-B cell crosstalk in triple negative breast cancer.
Ding S, Qiao N, Zhu Q, Tong Y, Wang S, Chen X, Tian Q, Xiao Y, Shen K
Cancer Commun (Lond) 2023 Jun;43(6):661-684. Epub 2023 May 9 doi: 10.1002/cac2.12429. PMID: 37158690Free PMC Article
Identification and Validation of a Novel Signature Based on NK Cell Marker Genes to Predict Prognosis and Immunotherapy Response in Lung Adenocarcinoma by Integrated Analysis of Single-Cell and Bulk RNA-Sequencing.
Song P, Li W, Guo L, Ying J, Gao S, He J
Front Immunol 2022;13:850745. Epub 2022 Jun 10 doi: 10.3389/fimmu.2022.850745. PMID: 35757748Free PMC Article
Tumor-infiltrating lymphocytes in the immunotherapy era.
Paijens ST, Vledder A, de Bruyn M, Nijman HW
Cell Mol Immunol 2021 Apr;18(4):842-859. Epub 2020 Nov 2 doi: 10.1038/s41423-020-00565-9. PMID: 33139907Free PMC Article
NK cells for cancer immunotherapy.
Shimasaki N, Jain A, Campana D
Nat Rev Drug Discov 2020 Mar;19(3):200-218. Epub 2020 Jan 6 doi: 10.1038/s41573-019-0052-1. PMID: 31907401

Recent systematic reviews

A systematic review and meta-analysis of CD22 CAR T-cells alone or in combination with CD19 CAR T-cells.
Fergusson NJ, Adeel K, Kekre N, Atkins H, Hay KA
Front Immunol 2023;14:1178403. Epub 2023 Apr 27 doi: 10.3389/fimmu.2023.1178403. PMID: 37180149Free PMC Article
Adoptive cell therapy in gynecologic cancers: A systematic review and meta-analysis.
Son J, George GC, Nardo M, Krause KJ, Jazaeri AA, Biter AB, Hong DS
Gynecol Oncol 2022 Jun;165(3):664-670. Epub 2022 Apr 7 doi: 10.1016/j.ygyno.2022.03.013. PMID: 35400527Free PMC Article
Evolving Strategies for the Treatment of T-Cell Lymphoma: A Systematic Review and Recent Patents.
Laribi K, Alani M, Truong C, de Materre AB
Recent Pat Anticancer Drug Discov 2018;13(3):308-340. doi: 10.2174/1574892813666180517102801. PMID: 29769011
L-Asparaginase for newly diagnosed extra-nodal NK/T-cell lymphoma: systematic review and meta-analysis.
Pokrovsky VS, Vinnikov D
Expert Rev Anticancer Ther 2017 Aug;17(8):759-768. Epub 2017 Jun 21 doi: 10.1080/14737140.2017.1344100. PMID: 28621166
Primary pituitary lymphoma: an update of the literature.
Tarabay A, Cossu G, Berhouma M, Levivier M, Daniel RT, Messerer M
J Neurooncol 2016 Dec;130(3):383-395. Epub 2016 Aug 31 doi: 10.1007/s11060-016-2249-z. PMID: 27581598

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