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Malignant Salivary Gland Neoplasm

MedGen UID:
65079
•Concept ID:
C0220636
•
Neoplastic Process
Synonyms: Cancer of Salivary Gland; Cancer of the Salivary Gland; Cancer, Salivary Gland; Cancers, Salivary Gland; Salivary Gland Cancer; Salivary Gland Cancers
SNOMED CT: Salivary gland cancer (255072001); Cancer of salivary gland (255072001); CA - Cancer of salivary gland (255072001); Malignant tumor of salivary gland (255072001)

Definition

A primary or metastatic malignant neoplasm that affects the major or minor salivary glands. Representative examples include carcinoma, lymphoma, and sarcoma. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMalignant Salivary Gland Neoplasm

Professional guidelines

PubMed

The role of fast neutron radiation therapy in the management of advanced salivary gland malignant neoplasms.
Buchholz TA, Laramore GE, Griffin BR, Koh WJ, Griffin TW
Cancer 1992 Jun 1;69(11):2779-88. doi: 10.1002/1097-0142(19920601)69:11<2779::aid-cncr2820691125>3.0.co;2-n. PMID: 1571909

Recent clinical studies

Etiology

Epidemiological and clinical characteristics of 407 salivary glands neoplasms in surgically treated patients in 2010-2020.
Jaremek-Ochniak W, Skulimowska J, Płachta I, Szafarowski T, Kukwa W
Otolaryngol Pol 2022 Sep 9;76(5):29-36. doi: 10.5604/01.3001.0015.9816. PMID: 36622126
Mucoepidermoid carcinoma of the head and neck in children.
Dombrowski ND, Wolter NE, Irace AL, Cunningham MJ, Mack JW, Marcus KJ, Vargas SO, Perez-Atayde AR, Robson CD, Rahbar R
Int J Pediatr Otorhinolaryngol 2019 May;120:93-99. Epub 2019 Feb 10 doi: 10.1016/j.ijporl.2019.02.020. PMID: 30772619
Clinical characteristics and treatment outcomes of primary and recurrent malignancy involving the salivary glands in children.
Qureshi SS, Bhagat M, Singhal N, Tathe N, Kembhavi S, Laskar S, Ramadwar M, Yadav P
Head Neck 2016 Jun;38(6):852-6. Epub 2015 Jul 15 doi: 10.1002/hed.24114. PMID: 25917761
Epithelial-myoepithelial carcinoma--review of clinicopathological and immunohistochemical features.
Dimitrijevic MV, Tomanovic NR, Jesic SD, Arsovic NA, Mircic AL, Krstic AM
Arch Iran Med 2015 Apr;18(4):218-22. PMID: 25841941
Myoepithelial carcinoma of intraoral minor salivary glands: a clinicopathological study of 7 cases and review of the literature.
Yang S, Li L, Zeng M, Zhu X, Zhang J, Chen X
Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2010 Jul;110(1):85-93. Epub 2010 May 21 doi: 10.1016/j.tripleo.2010.02.023. PMID: 20488733

Diagnosis

Bronchial salivary gland-type intraductal carcinoma with KIAA1217::RET gene fusion composed of intercalated and oncocytic components.
Song L, Cheng XK, Yang Z, Ji XB, Zhou XL, Cheng HX, Lin DL
Virchows Arch 2023 Apr;482(4):789-795. Epub 2022 Nov 21 doi: 10.1007/s00428-022-03456-8. PMID: 36414804
Epidemiological and clinical characteristics of 407 salivary glands neoplasms in surgically treated patients in 2010-2020.
Jaremek-Ochniak W, Skulimowska J, Płachta I, Szafarowski T, Kukwa W
Otolaryngol Pol 2022 Sep 9;76(5):29-36. doi: 10.5604/01.3001.0015.9816. PMID: 36622126
Mucoepidermoid carcinoma. An update and review of the literature.
Peraza A, Gómez R, Beltran J, Amarista FJ
J Stomatol Oral Maxillofac Surg 2020 Dec;121(6):713-720. Epub 2020 Jun 18 doi: 10.1016/j.jormas.2020.06.003. PMID: 32565266
Mucoepidermoid carcinoma of the head and neck in children.
Dombrowski ND, Wolter NE, Irace AL, Cunningham MJ, Mack JW, Marcus KJ, Vargas SO, Perez-Atayde AR, Robson CD, Rahbar R
Int J Pediatr Otorhinolaryngol 2019 May;120:93-99. Epub 2019 Feb 10 doi: 10.1016/j.ijporl.2019.02.020. PMID: 30772619
Epithelial-myoepithelial carcinoma--review of clinicopathological and immunohistochemical features.
Dimitrijevic MV, Tomanovic NR, Jesic SD, Arsovic NA, Mircic AL, Krstic AM
Arch Iran Med 2015 Apr;18(4):218-22. PMID: 25841941

Prognosis

Acinic cell carcinoma of the posterior buccal mucosa: A rare case report.
Babu SS, Sunil S, Prathap A, Mathew AL
J Cancer Res Ther 2020 Apr-Jun;16(3):675-679. doi: 10.4103/jcrt.JCRT_399_18. PMID: 32719290
Mucoepidermoid carcinoma of the head and neck in children.
Dombrowski ND, Wolter NE, Irace AL, Cunningham MJ, Mack JW, Marcus KJ, Vargas SO, Perez-Atayde AR, Robson CD, Rahbar R
Int J Pediatr Otorhinolaryngol 2019 May;120:93-99. Epub 2019 Feb 10 doi: 10.1016/j.ijporl.2019.02.020. PMID: 30772619
Clinical characteristics and treatment outcomes of primary and recurrent malignancy involving the salivary glands in children.
Qureshi SS, Bhagat M, Singhal N, Tathe N, Kembhavi S, Laskar S, Ramadwar M, Yadav P
Head Neck 2016 Jun;38(6):852-6. Epub 2015 Jul 15 doi: 10.1002/hed.24114. PMID: 25917761
Epithelial-myoepithelial carcinoma--review of clinicopathological and immunohistochemical features.
Dimitrijevic MV, Tomanovic NR, Jesic SD, Arsovic NA, Mircic AL, Krstic AM
Arch Iran Med 2015 Apr;18(4):218-22. PMID: 25841941
Myoepithelial carcinoma of intraoral minor salivary glands: a clinicopathological study of 7 cases and review of the literature.
Yang S, Li L, Zeng M, Zhu X, Zhang J, Chen X
Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2010 Jul;110(1):85-93. Epub 2010 May 21 doi: 10.1016/j.tripleo.2010.02.023. PMID: 20488733

Clinical prediction guides

Effect of Matrigel on adenoid cystic carcinoma cell line differentiation.
Marques MM, Martins MD, França CM
Int J Exp Pathol 2006 Dec;87(6):405-10. doi: 10.1111/j.1365-2613.2006.00498.x. PMID: 17222208Free PMC Article
Epithelial-myoepithelial carcinoma of the lung: immunohistochemical and ultrastructural observations and review of the literature.
Wilson RW, Moran CA
Hum Pathol 1997 May;28(5):631-5. doi: 10.1016/s0046-8177(97)90088-5. PMID: 9158714

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