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Disease of liver

MedGen UID:
9792
•Concept ID:
C0023895
•
Disease or Syndrome
Synonyms: Disease, Liver; Diseases, Liver; Liver Disease; Liver Diseases
SNOMED CT: Hepatopathy (235856003); Liver disease (235856003); Disorder of liver (235856003); LD - Liver disease (235856003); Disease of liver (235856003)

Definition

A non-neoplastic or neoplastic disorder that affects the liver parenchyma and intrahepatic bile ducts. Representative examples of non-neoplastic disorders include hepatitis, cirrhosis, cholangitis, and polycystic liver disease. Representative examples of neoplastic disorders include hepatocellular adenoma, hepatocellular carcinoma, intrahepatic cholangiocarcinoma, lymphoma, and angiosarcoma. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDisease of liver

Professional guidelines

PubMed

Management of Hepatocellular Carcinoma: A Review.
Brown ZJ, Tsilimigras DI, Ruff SM, Mohseni A, Kamel IR, Cloyd JM, Pawlik TM
JAMA Surg 2023 Apr 1;158(4):410-420. doi: 10.1001/jamasurg.2022.7989. PMID: 36790767
EASL Clinical Practice Guidelines: Drug-induced liver injury.
European Association for the Study of the Liver. Electronic address: easloffice@easloffice.eu; Clinical Practice Guideline Panel: Chair:; Panel members; EASL Governing Board representative:
J Hepatol 2019 Jun;70(6):1222-1261. Epub 2019 Mar 27 doi: 10.1016/j.jhep.2019.02.014. PMID: 30926241
ACG Clinical Guideline: Alcoholic Liver Disease.
Singal AK, Bataller R, Ahn J, Kamath PS, Shah VH
Am J Gastroenterol 2018 Feb;113(2):175-194. Epub 2018 Jan 16 doi: 10.1038/ajg.2017.469. PMID: 29336434Free PMC Article

Recent clinical studies

Etiology

Wilson disease in Northern Portugal: a long-term follow-up study.
Garrido I, Marques M, Liberal R, Cardoso H, Lopes S, Macedo G
Orphanet J Rare Dis 2022 Feb 23;17(1):82. doi: 10.1186/s13023-022-02245-5. PMID: 35197085Free PMC Article
Characteristics and risk of chronic graft-versus-host disease of liver in allogeneic hematopoietic stem cell transplant recipients.
Chen CT, Liu CY, Yu YB, Liu CJ, Hsiao LT, Gau JP, Chiou TJ, Liu JH, Liu YC
PLoS One 2017;12(9):e0185210. Epub 2017 Sep 21 doi: 10.1371/journal.pone.0185210. PMID: 28934311Free PMC Article
Fibropolycystic disease of the liver and kidney in Oman.
Al-Lawati TT
Arab J Gastroenterol 2013 Dec;14(4):173-5. Epub 2013 Dec 23 doi: 10.1016/j.ajg.2013.11.004. PMID: 24433648
Tuberculosis and liver disease: management issues.
Sonika U, Kar P
Trop Gastroenterol 2012 Apr-Jun;33(2):102-6. doi: 10.7869/tg.2012.25. PMID: 23025055
A survey of acute and chronic disease associated with Yersinia enterocolitica infection. A Norwegian 10-year follow-up study on 458 hospitalized patients.
Saebø A, Lassen J
Scand J Infect Dis 1991;23(5):517-27. doi: 10.3109/00365549109105172. PMID: 1767249

Diagnosis

Wilson disease in Northern Portugal: a long-term follow-up study.
Garrido I, Marques M, Liberal R, Cardoso H, Lopes S, Macedo G
Orphanet J Rare Dis 2022 Feb 23;17(1):82. doi: 10.1186/s13023-022-02245-5. PMID: 35197085Free PMC Article
Fibropolycystic disease of the liver and kidney in Oman.
Al-Lawati TT
Arab J Gastroenterol 2013 Dec;14(4):173-5. Epub 2013 Dec 23 doi: 10.1016/j.ajg.2013.11.004. PMID: 24433648
Fibrocystic disease of liver and pancreas; under-recognized features of the X-linked ciliopathy oral-facial-digital syndrome type 1 (OFD I).
Chetty-John S, Piwnica-Worms K, Bryant J, Bernardini I, Fischer RE, Heller T, Gahl WA, Gunay-Aygun M
Am J Med Genet A 2010 Oct;152A(10):2640-5. doi: 10.1002/ajmg.a.33666. PMID: 20818665Free PMC Article
A survey of acute and chronic disease associated with Yersinia enterocolitica infection. A Norwegian 10-year follow-up study on 458 hospitalized patients.
Saebø A, Lassen J
Scand J Infect Dis 1991;23(5):517-27. doi: 10.3109/00365549109105172. PMID: 1767249
Nuclear medicine and ultrasound; correlation in diagnosis of disease of liver and biliary tract.
Lomonaco A, Kline P, Halpern S, Leopold G
Semin Nucl Med 1975 Oct;5(4):307-24. doi: 10.1016/s0001-2998(75)80019-5. PMID: 1209273

Therapy

Wilson disease in Northern Portugal: a long-term follow-up study.
Garrido I, Marques M, Liberal R, Cardoso H, Lopes S, Macedo G
Orphanet J Rare Dis 2022 Feb 23;17(1):82. doi: 10.1186/s13023-022-02245-5. PMID: 35197085Free PMC Article
Characteristics and risk of chronic graft-versus-host disease of liver in allogeneic hematopoietic stem cell transplant recipients.
Chen CT, Liu CY, Yu YB, Liu CJ, Hsiao LT, Gau JP, Chiou TJ, Liu JH, Liu YC
PLoS One 2017;12(9):e0185210. Epub 2017 Sep 21 doi: 10.1371/journal.pone.0185210. PMID: 28934311Free PMC Article
TLR4-dependant immune response, but not hepatitis B virus reactivation, is important in radiation-induced liver disease of liver cancer radiotherapy.
Wu ZF, Zhou XH, Hu YW, Zhou LY, Gao YB, Peng XH, Yang XH, Zhang JY, Hu Y, Zeng ZC
Cancer Immunol Immunother 2014 Mar;63(3):235-45. Epub 2013 Dec 15 doi: 10.1007/s00262-013-1504-9. PMID: 24337704
Tuberculosis and liver disease: management issues.
Sonika U, Kar P
Trop Gastroenterol 2012 Apr-Jun;33(2):102-6. doi: 10.7869/tg.2012.25. PMID: 23025055
An epidemic of veno-occlusive disease of liver in central India.
Tandon BN, Tandon HD, Tandon RK, Narndranathan M, Joshi YK
Lancet 1976 Aug 7;2(7980):271-2. doi: 10.1016/s0140-6736(76)90727-3. PMID: 59849

Prognosis

Wilson disease in Northern Portugal: a long-term follow-up study.
Garrido I, Marques M, Liberal R, Cardoso H, Lopes S, Macedo G
Orphanet J Rare Dis 2022 Feb 23;17(1):82. doi: 10.1186/s13023-022-02245-5. PMID: 35197085Free PMC Article
Characteristics and risk of chronic graft-versus-host disease of liver in allogeneic hematopoietic stem cell transplant recipients.
Chen CT, Liu CY, Yu YB, Liu CJ, Hsiao LT, Gau JP, Chiou TJ, Liu JH, Liu YC
PLoS One 2017;12(9):e0185210. Epub 2017 Sep 21 doi: 10.1371/journal.pone.0185210. PMID: 28934311Free PMC Article
Fibropolycystic disease of the liver and kidney in Oman.
Al-Lawati TT
Arab J Gastroenterol 2013 Dec;14(4):173-5. Epub 2013 Dec 23 doi: 10.1016/j.ajg.2013.11.004. PMID: 24433648
A survey of acute and chronic disease associated with Yersinia enterocolitica infection. A Norwegian 10-year follow-up study on 458 hospitalized patients.
Saebø A, Lassen J
Scand J Infect Dis 1991;23(5):517-27. doi: 10.3109/00365549109105172. PMID: 1767249
Nuclear medicine and ultrasound; correlation in diagnosis of disease of liver and biliary tract.
Lomonaco A, Kline P, Halpern S, Leopold G
Semin Nucl Med 1975 Oct;5(4):307-24. doi: 10.1016/s0001-2998(75)80019-5. PMID: 1209273

Clinical prediction guides

Characteristics and risk of chronic graft-versus-host disease of liver in allogeneic hematopoietic stem cell transplant recipients.
Chen CT, Liu CY, Yu YB, Liu CJ, Hsiao LT, Gau JP, Chiou TJ, Liu JH, Liu YC
PLoS One 2017;12(9):e0185210. Epub 2017 Sep 21 doi: 10.1371/journal.pone.0185210. PMID: 28934311Free PMC Article
Association of Helicobacter pylori with hepatobiliary stone disease, a prospective case control study.
Dar MY, Ali S, Raina AH, Raina MA, Shah OJ, Shah MA, Mudassar S
Indian J Gastroenterol 2016 Sep;35(5):343-346. Epub 2016 Sep 16 doi: 10.1007/s12664-016-0675-7. PMID: 27633033
Fibropolycystic disease of the liver and kidney in Oman.
Al-Lawati TT
Arab J Gastroenterol 2013 Dec;14(4):173-5. Epub 2013 Dec 23 doi: 10.1016/j.ajg.2013.11.004. PMID: 24433648
A survey of acute and chronic disease associated with Yersinia enterocolitica infection. A Norwegian 10-year follow-up study on 458 hospitalized patients.
Saebø A, Lassen J
Scand J Infect Dis 1991;23(5):517-27. doi: 10.3109/00365549109105172. PMID: 1767249
Nuclear medicine and ultrasound; correlation in diagnosis of disease of liver and biliary tract.
Lomonaco A, Kline P, Halpern S, Leopold G
Semin Nucl Med 1975 Oct;5(4):307-24. doi: 10.1016/s0001-2998(75)80019-5. PMID: 1209273

Recent systematic reviews

Primary hepatic gastrointestinal stromal tumor with right adrenal gland invasion: A case report and systematic literature review.
Xu L, Zhang M, Xu M
Medicine (Baltimore) 2019 May;98(20):e15482. doi: 10.1097/MD.0000000000015482. PMID: 31096446Free PMC Article

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