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Neoplasm of the large intestine

MedGen UID:
3171
Concept ID:
C0009404
Neoplastic Process
Synonyms: Colorectal neoplasm; Colorectal Neoplasms
SNOMED CT: Neoplasm of large intestine (126837005); Tumor of large intestine (126837005)
 
Related genes: FLCN, MLH3, RAD54B, DLC1, AXIN2, TP53, TLR2, AURKA, SRC, PTPRJ, PTPN12, PLA2G2A, PIK3CA, PDGFRL, NRAS, MCC, FGFR3, EP300, DCC, CTNNB1, BUB1B, BUB1, BRAF, CCND1, BAX, APC, AKT1
 
HPO: HP:0100834
Monarch Initiative: MONDO:0005335

Definition

The presence of a neoplasm of the large intestine. [from HPO]

Term Hierarchy

Professional guidelines

PubMed

Cervantes A, Adam R, Roselló S, Arnold D, Normanno N, Taïeb J, Seligmann J, De Baere T, Osterlund P, Yoshino T, Martinelli E; ESMO Guidelines Committee. Electronic address: clinicalguidelines@esmo.org
Ann Oncol 2023 Jan;34(1):10-32. Epub 2022 Oct 25 doi: 10.1016/j.annonc.2022.10.003. PMID: 36307056
Lordick F, Carneiro F, Cascinu S, Fleitas T, Haustermans K, Piessen G, Vogel A, Smyth EC; ESMO Guidelines Committee. Electronic address: clinicalguidelines@esmo.org
Ann Oncol 2022 Oct;33(10):1005-1020. Epub 2022 Jul 29 doi: 10.1016/j.annonc.2022.07.004. PMID: 35914639
Syngal S, Brand RE, Church JM, Giardiello FM, Hampel HL, Burt RW; American College of Gastroenterology
Am J Gastroenterol 2015 Feb;110(2):223-62; quiz 263. Epub 2015 Feb 3 doi: 10.1038/ajg.2014.435. PMID: 25645574Free PMC Article

Recent clinical studies

Diagnosis

Owen DR, Wong HL, Bonakdar M, Jones M, Hughes CS, Morin GB, Jones SJM, Renouf DJ, Lim H, Laskin J, Marra M, Yip S, Schaeffer DF
Cold Spring Harb Mol Case Stud 2018 Apr;4(2) Epub 2018 Apr 2 doi: 10.1101/mcs.a002535. PMID: 29438965Free PMC Article
Shindo K
Am J Proctol 1977 Aug;28(4):57-64. PMID: 888945

Therapy

Owen DR, Wong HL, Bonakdar M, Jones M, Hughes CS, Morin GB, Jones SJM, Renouf DJ, Lim H, Laskin J, Marra M, Yip S, Schaeffer DF
Cold Spring Harb Mol Case Stud 2018 Apr;4(2) Epub 2018 Apr 2 doi: 10.1101/mcs.a002535. PMID: 29438965Free PMC Article

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